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Antibiotic Residue In
Milk
Milk and
Slaughter Withhold Times
If you have given a goat a drug, you may not sell their milk
or meat until the drug is completely out of their system. This to prevent people who eat the food or
drink the milk, from getting resistant to antibiotics by being overexposed to
them. You must scrupulously adhere to
withhold times, yet it is often difficult to know what they should be, since
many drugs are labeled for other animals, and the withdrawal time for a goat
may be very different.
You should consult your veterinarian about withdrawal times, and if you vet does not know what the withhold time should be, he or she can get that information from FARAD (Food Animal Residue Avoidance Databank) at 1-888-us-farad, or go to www.farad.org. Many withdrawal times on drugs for goats can also be found in Scott Haskell's on-line manual entitled Small Ruminant Clinical Diagnosis and Therapy, http://www.rmncsba.org/SMALLRUMINANT.pdf It is very slow to load, especially if you have dial-up internet service, but it is an excellent resource. See the medical section of this website if you have questions about extra-label drug use. Testing the milk
for antibiotics
Even if you know what the recommended withhold time is, you
cannot be sure that a drug will leave the goat’s system when the withhold time
says it will. If an animal has been ill,
it's whole system can be slowed down, and will not process the drug as quickly
as it will in a well goat. Make sure
that you do not ship milk from a treated goat until a sample has been sent with
your trucker and you get a call back that there are no antibiotics in the milk.
(Haskell, Mastitis)
Wisconsin Regulations regarding drug residues in meat: ATCP 55.07 Drug residues in milk: ATCP 60.19 and ATCP 97.23. Common mistakes that cause antibiotic contamination in milk1. Milk from a treated goat was accidentally routed into the
pipeline.
2. A “not completely dry” goat was given an intermammary antibiotic to prevent mastitis. The farmer intended to move her to the dry goat shed, but somehow she was unintentionally milked with the herd. 3. The same milking unit was used to milk an antibiotic-treated goat before milking untreated goats. 4. Lactating goats were purchased, and the new owner was unaware of recent antibiotic treatments given by the previous owner. 5. One half of the udder was treated for mastitis and the producer didn’t ship milk from the treated half, but they did ship milk from the untreated half thinking it was safe. 6. A minimilker, with milk from a treated goat, was tipped over, or overflowed, and some of the milk backed up into the system. 7. The farmer normally milked the antibiotic-treated goats last, removing the milk line from the bulk tank before doing it, but this time he forgot to remove the milk line. 8. Medicated feed meant for non-lactating animals was accidentally mixed into the lactating goat feed. 9. Goats drank from a medicated footbath. 10. A goat in the dry goat pen is given a treatment to prevent mastitis. She aborts. The farmer forgets that the goat has antibiotics in her and milks her. 11. Severely ill goats were treated, and although the withhold time passed, the drug had not moved out of their body because they were so ill their system was not working properly. (Adapted from MDA) What to do if you think you milked a goat on antibiotics by mistakeIf it is pick up day, do not allow the trucker to pick up
milk that may have antibiotic in it. If
he arrives, ask him to test for antibiotics before he takes the milk. If the trucker cannot test for antibiotics,
then do not let him take the milk.
Instead, drive a sample to the trucking company headquarters or nearest
testing facility and have a test run.
AgSource does not run tests on Saturday, Sunday, or holidays, but the
trucking companies generally have one at their facility, and can run it any
time.
If the test positive, write down the amount of milk in the tank, then dump the milk and clean the tank. Call your field man and tell him what happened. Some of the cheese plants will pay for one dump per year. If your company does not do this, then call your insurance agent and file a claim. This is why you must always carry dairy protection insurance. Consequences
of shipping milk with antibiotics in it
If milk is positive for antibiotics and you let it get
picked up and mixed with the other milk in the truck, you are liable for all of
the milk in the truck, as well as other expenses such as the cost of disposing
of that milk, repeated testing, and any other costs incurred due to your
negligence. You should carry dairy protection
insurance for this, as a truckload of milk is extremely expensive. (Interview with Harvey Ziemer, Filed Man for
Kolb Lena Cheese)
On-farm
test kits for antibiotic residue
According to the Ontario Ministry of Agriculture, Food and
Rural Affairs:
"Currently, there are a variety of screening tests on the market suitable for on-farm testing. Each test has its own benefits and limitations in cost, speed and sensitivity. The major suppliers for the North American market are Idexx Laboratories, CHARM Sciences and DSM Food Specialties. Apocrine Secretion (Goat) v. Alveolar Secretion (Cow)Goat milk production is an apocrine secretion.
(Apocrine Secretion is a type of glandular secretion in
which the tip of the secreting cell is released along with the milk.)
Cow milk production is an alveolar merocrine secretion. Alveolar merocrine secretion is a type of secretion in which
the honeycomb-type cells remain undamaged during the secretion of the milk, so
only milk is released.
Why is this important?
Goat milk has cytoplasmic particulate debris
and epithelial cells shed along with the milk.
Cow milk does not. (see definition section below.) Therefore, if
the somatic cell count of goat milk depends only upon counting numbers of
cells, with no effort to sort out the type of cell, the goat milk will appear
to have a higher somatic cell count than cow milk.
The debris and epithelial cells are about the same size as the white blood cells that appear where there is disease, and unless you have stains that differentiate between types of cells, you may have a falsely high somatic cell count, especially if the testing company uses machinery calibrated for cows. As a practical matter, AgSource said, many small testing companies cannot afford to have a separate machine calibrated just for goats, so you can expect higher counts. The solution: ask your legislators to raise the test limits for goats in the state statutes. Definitions:
Cytoplasmic particulate debris=debris particles from the
protoplasm outside the nucleus of a cell
Epithelial cells make up the membranous tissue covering most internal and external surfaces of the body and its organs T White blood cells are cells that contain a nucleus (have DNA) and cytoplasm and help protect the body from infection and disease. Somatic cell: Any body cell other than a germ cell (Germ cells are ovum or sperm.) Somatic Cell Count (SCC) is the number of body cells in a quantity of milk. What we are looking for in somatic cell counts is evidence
of infection (mastitis). Where there is
infection, you will find an increase in the number of white blood cells, since
their duty is to protect the body from infection and disease. Therefore, the perfect SCC test for goats
would count only the white blood cells. The green stain, or direct microscopic
(DMSCC) test is the only test that does that at this time.
(Haskell, Caprine Milk Quality and Mastitis) Average peak
pounds of milk per day/goat
10-15 lbs. (at 8 lbs. per gallon, that is 1.25 to 1.875
gallons per day)
Dairy Practices Council “Guidelines For The Design, Installation, and Cleaning of Small Ruminant Milking Systems” Breeding for conformation, increased milk production and componentsA Quebec study took 26 goat herds where farmers followed
selection protocol-based traits that were balanced to 60% production and 40%
conformation. The traits were: Milk
protein, fat yield, fat and protein percentage, 8 conformation traits of
general appearance, leg strength, dairy character, body capacity, median
suspensory ligament, front and rear attachment of the udder, and teat
quality. They made their selections of
the young stock based on the performance of their mothers and other related
does. After 4 years there was an
increase of 34.1-39.6 lbs of milk per goat per year, and annual average
increase of 0.7-1.14 lbs. of butterfat and 0.7-1.10 lbs. of milk protein per
goat. This increased income by
$1400-1600 per year per farm (minimum). http://www.uvm.edu/sustainableagriculture/SmRumNewsletterWinter2006.pdf
Colostrum
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|
Common
Name |
Scientific
Name |
Principal
Toxin |
|
White
snakeroot |
Eupatorium
rugosum |
Acetylbenzofurans
(tremetol) |
|
Rayless
golden rod |
Isocoma
pluraflora |
Acetylbenzofurans
(tremetol) |
|
Groundsels,
senecio |
Senecio
spp. |
Pyrrolizidine
alkaloids |
|
Rattle
pod |
Crotolaria
spp. |
Pyrrolizidine
alkaloids |
|
Hound's
tongue |
Cynoglossum
spp. |
Pyrrolizidine
alkaloids |
|
Fiddleneck |
Amsinckia
intermedia |
Pyrrolizidine
alkaloids |
|
Comfrey |
Symphytum
spp. |
Pyrrolizidine
alkaloids |
|
Heliotrope |
Heliotropium
spp. |
Pyrrolizidine
alkaloids |
|
Viper's
bugloss |
Echium
spp. |
Pyrrolizidine
alkaloids |
|
Mustards,
rape, cabbage |
Brassica
spp. |
Glucosinolates* |
|
Horse
radish |
Amoracia
spp. |
Glucosinolates* |
|
Radish |
Raphanus
spp. |
Glucosinolates* |
|
Water
cress |
Nasturtium
officinale |
Glucosinolates* |
|
Poison
hemlock |
Conium
maculatum |
Piperidine
alkaloids (coniine) |
|
Tobacco |
Nicotiana
spp. |
Piperidine
alkaloids (coniine) |
|
Locoweeds |
Astragalus,
Oxytropis spp. |
Indolizidine
alkaloids (swainsonine) |
|
Lupine |
Lupinus
spp. |
Quinolizidine
alkaloids (anagyrine) |
|
Bitterweeds |
Helenium,
Hymenoxys spp. |
Sesquiterpene
lactones* |
|
Bracken
fern |
Pteridium
aquilinum |
Ptaquiloside |
|
Buttercups |
Ranunculus
spp. |
Protoanemonins* |
|
Onions,
garlic |
Allium
spp. |
N-propyl
disulphide* |
|
Autumn
crocus |
Colchicum
spp. |
Alkaloids
(colchicine) |
|
Avocado |
Persea
|
Unknown
toxin |
|
Sage |
Artemisia
spp. |
Monoterpenes,
diterpenes* |
|
Marijuana |
Cannabis
sativa |
Cannabinol |
|
*
These plants impart an abnormal flavor to milk. |
||
from Knight, A.
P. and Walter, R. G., Plants Affecting the Mammary Gland, http://www.ivis.org/special_books/Knight/chap10/chapter.asp?LA=1, accessed